Synthesis, antimicrobial, antioxidant and docking study of novel isoxazoline derivatives

Synthesis, Antimicrobial and Docking Studies of Novel Benzotriazole Derivatives

In view of the biological and clinical importance of Benzotriazole compounds, some new derivatives were synthesized and characterized on the basis of analytical and spectral data. All the new compounds were evaluated at 500μg/ml, 250μg/ml and 100μg/ml for the antibacterial and antifungal activity. Some of the compounds showed moderate to good antimicrobial activity against gram positive and gra...

antioxidant and antimicrobial activity of allium jesdianum extract

چکیده بررسی فعالیت ضد اکسیدانی و ضدمیکروبی عصاره گیاه بن سرخ (allium jesdianum) به کوشش: زهرا مقیمی هدف از این تحقیق بررسی میزان ترکیبات فنولی کل، ترکیبات فلاوونوئیدی کل، فعالیت ضداکسیدانی و ضدمیکروبی عصاره ی گیاه تازه و خشک بن سرخ بود. استخراج عصاره به روش های غوطه وری، استفاده از همزن مغناطیسی، دستگاه مایکروویو، امواج فراصوت و گرمادهی مقاومتی و با استفاده از متانول، اتانول و آب به عنوا...

Synthesis and estimations of antimicrobial properties of novel pyrazoline derivatives

Chalcones are the condensation product of acetophenone in combination with aromatic aldehydes in the presence of strong base. Chalcones and their metal complexes having prominent role in modern coordination chemistry. These compounds possessing novel structural features, interesting spectral and magnetic properties, have been the subject of intensive research due to their importance in medical,...

synthesis and antimicrobial study of some novel 1,2,3-triazol derivatives

Facile Synthesis of Novel Coumarin Derivatives, Antimicrobial Analysis, Enzyme Assay, Docking Study, ADMET Prediction and Toxicity Study.

The work reports the synthesis under solvent-free condition using the ionic liquid [Et₃NH][HSO₄] as a catalyst of fifteen novel 3-((dicyclohexylamino)(substituted phenyl/heteryl)-methyl)-4-hydroxy-2H-chromen-2-onederivatives 4a-o as potential antimicrobial agents. The structures of the synthesized compounds were confirmed by IR, ¹H-NMR, 13C-NMR, mass spectral studies and elemental analyses. All...